High Dietary Antioxidant Intake Associated With Lower Risk For Early AMD

Medscape (6/14, Barclay) reported, “High dietary intake of antioxidants is associated with a lower risk for early age-related macular degeneration (AMD) in genetically predisposed individuals,” according to a study published in the June issue of the Archives of Ophthalmology. In a study of 2,167 individuals over the age of 55 who were at risk of AMD, researchers found “a possible biological interaction between the CFH Y402H genotype and intakes of zinc, β-carotene, lutein/zeaxanthin, and eicosapentaenoic/docosahexaenoic acid (EPA/DHA), and between the LOC387715 A69S genotype and zinc and EPA/DHA, based on significant synergy indices (P < .05 for all).” Notably, “participants who were homozygous for CFH Y402H and had dietary zinc intake in the highest tertile had a reduction in HR for early AMD from 2.25 to 1.27.”